Development of the RTI item bank on risk of bias and precision of observational studies [electronic resource] / prepared for Agency for Healthcare Research and Quality U.S. Department of Health and Human Services ; prepared by RTI International-University of North Carolina Evidence-based Practice Center ; investigators, Meera Viswanathan, Nancy D. Berkman
- Viswanathan, Meera
- Rockville, MD : Agency for Healthcare Research and Quality, 
- Physical Description:
- 1 online resource (1 PDF file (various pagings)) : ill
- Additional Creators:
- Berkman, Nancy D., United States. Agency for Health Care Policy and Research, and RTI International-University of North Carolina Evidence-based Practice Center
- Methods research report and AHRQ publication ; no. 11-EHC028-EF
- Restrictions on Access:
- License restrictions may limit access.
- OBJECTIVE: To create a practical and validated item bank for evaluating the risk of bias and precision of observational studies of interventions or exposures included in systematic evidence reviews. STUDY DESIGN AND SETTING: The item bank was created based on 1,492 questions included in earlier instruments, organized by the quality domains identified by Deeks and colleagues. Items were eliminated and refined through face validity, cognitive, content validity, and interrater reliability testing. RESULTS: The resulting RTI item bank, consisting of 29 questions for evaluating the risk of bias and precision of observational studies of interventions or exposures: (1) captures all of the domains critical for evaluating this type of research; (2) is comprehensive and can be easily lifted "off the shelf" by different researchers; (3) can be adapted to different topic areas and study types (e.g., cohort, case control, cross-sectional and case series studies); and (4) provides sufficient instruction to apply the tool to varied topics. CONCLUSIONS: One bank of items, with specific instructions for focusing abstractor evaluations, can be created to judge the risk of bias and precision of the variety of observational studies that may be used in systematic and comparative effectiveness reviews.
- "September 2011."
- Bibliography Note:
- Includes bibliographical references.
- Funding Information:
- Contract No. 290-2007-10056-I
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