Actions for Immunogenetics: Advances and Education [electronic resource] : The First Congress of the Slovak Foundation

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Immunogenetics: Advances and Education [electronic resource] : The First Congress of the Slovak Foundation / edited by Alejandro J. Madrigal, Margita Bencová, Derek Middleton, Dominique Charron, Tibor Nánási

Author
Madrigal, Alejandro J.
Additional Titles
Proceedings of the NATO Advanced Research Workshop, held in Castá-Papiernicka, Bratislava, Slovak Republic, September 5-9, 1996
Published
Dordrecht : Springer Netherlands : Imprint: Springer, 1997.
Physical Description
XXVI, 265 pages : online resource
Additional Creators
Bencová, Margita, Middleton, Derek, Charron, D. (Dominique), Nánási, Tibor, and SpringerLink (Online service)
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Series
Contents
The Slovak Foundation: Education in Immunogenetics -- Accreditation in Europe -- Accreditation - A Personal View -- HLA Diversity of Alleles and Haplotypes. The Contribution of the 12th International Histocompatibility Workshop -- The Associated Polymorphism of HLA-DR2: Genotyping of DRB1, DRB5, DQB1 loci in Slovakia Caucasian Population -- Paternity Testing—Past, Present, Future -- The Molecular Basis of the HLA Association in Celiac Disease. A Model Disease for Type 1 Diabetes and other HLA Associated Disease -- Immunogenetics of Graves’ Disease — An Overview -- Assessing Prognosis in Rheumatoid Arthritis Using Monoclonal Antibodies and Flow Cytometry -- Hashimoto’s Thyroiditis and HLA-DR-DQ Haplotypes Associated with Control of Disease Resistance -- Detection of the Tick Borne Encephalitis Virus in the Ticks and the Study of HLA Associations with the Tick Borne Encephalitis Onset -- Immunogenetic Prognosis for Susceptibility to the Stomach Cancer Onset -- Permissible Mismatches, Acceptable Mismatches and Tolerance: New Trends in Decision Making -- The Application of Cellular Tests in the Selection of Unrelated Donors for Bone Marrow Transplantation -- HLA Typing at the Molecular Level in the Process of Donor Selection for Bone Marrow Transplantation -- Bone Marrow Transplantation at Princess Margaret Hospital, University of Toronto -- Transatlantic Bone Marrow Transplantation -- The Role of HLA-DR, DQ, DP Subregions Compatibility in the Induction of Cytotoxic T Lymphocytes in Kidney Transplantation from Living Donor -- Microsatellite Testing of the Major Histocompatibility Complex in Human -- NCOI Polymorphism within the TNF? Promotor Region and the First Intron of TNFß Gene in Association with DRB1 Specificities in Healthy Volunteers -- HLA in Kidney Transplantation -- Facts and Figures of Eurotransplant -- Affect of Class I and Class II HLA Groups on Graft and Patient Survivals in Kidney Transplant Patients -- The First Kidney Transplantation in Slovakia -- HLA Class I and Class II Matched Donor Material for Improved Corneal Allograft Survival -- HLA Typing from Serology to Molecular Biology -- HLA-DP Epitope Typing Using Monoclonal Antibodies -- Evolution of Molecular HLA Typing -- Internet Application in the Histocompatibility Laboratory -- Author’s Index.
Summary
The objective underlying this book is educational, aiming to advance the development of immunogenetics/histocompatibility and to encourage the international collaboration that is so necessary for the international transplant programme and for research into the genetic predisposition to develop diseases associated with genes in the HLA complex. The revolution in high-tech molecular biological genome technology has given rise to a prodigious development of molecular techniques for the polymorphism analysis of HLA and the subsequent application of research results in clinical practice. Many new alleles have been discovered and different mechanisms have been shown to generate these new alleles. This has improved both diagnostic efficiency and increased the success of transplantation. Topics covered include HLA associated susceptibility to autoimmune disease. Strategies and efficiency of BMDW and benefit of collaboration. Optimum selection of unrelated bone marrow donor and extension of the pool of suitable donors by determination of possible mismatches. Identification of sibling pairs using microsatellites across the HLA region. HLA in kidney transplantation. Eurotransplant facts and figures. HLA typing from serology to molecular biology. Evolution of DNA based typing in HLA laboratories. HLA and paternity testing.
Subject(s)
ISBN
9789401154864
Digital File Characteristics
text file PDF
Note
AVAILABLE ONLINE TO AUTHORIZED PSU USERS.
Part Of
Springer eBooks
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