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Programmed assembly of nanoscale structures using peptoids [electronic resource].

Published
Washington, D.C. : United States. Dept. of Energy, 2011.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy.
Physical Description
48 pages : digital, PDF file
Additional Creators
Sandia National Laboratories, United States. Department of Energy, and United States. Department of Energy. Office of Scientific and Technical Information
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Summary
Sequence-specific polymers are the basis of the most promising approaches to bottom-up programmed assembly of nanoscale materials. Examples include artificial peptides and nucleic acids. Another class is oligo(N-functional glycine)s, also known as peptoids, which permit greater sidegroup diversity and conformational control, and can be easier to synthesize and purify. We have developed a set of peptoids that can be used to make inorganic nanoparticles more compatible with biological sequence-specific polymers so that they can be incorporated into nucleic acid or other biologically based nanostructures. Peptoids offer degrees of modularity, versatility, and predictability that equal or exceed other sequence-specific polymers, allowing for rational design of oligomers for a specific purpose. This degree of control will be essential to the development of arbitrarily designed nanoscale structures.
Report Numbers
E 1.99:sand2011-0899
sand2011-0899
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Note
Published through SciTech Connect.
02/01/2011.
"sand2011-0899"
Buffleben, George M.; Kent, Michael Stuart; Ren, Jianhua; Russell, Scott; Morishetti, Kiran; Robinson, David B.; Zuckermann, Ronald N.; Hjelm, Rex P.
Funding Information
AC04-94AL85000
View MARC record | catkey: 13808888