Metabolism of benzo(a)pyrene [electronic resource] : comparison of rodent liver and embryonic cells in tissue culture. [Rats, hamsters, mice].

Published: Oak Ridge, Tenn. : Oak Ridge National Laboratory, 1977.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy.
Physical Description: Pages: 23 : digital, PDF file
Additional Creators: Oak Ridge National Laboratory and United States. Department of Energy. Office of Scientific and Technical Information

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Summary

Rats, hamsters, and mice were given intraperitoneal injections of methylcholanthrene and were killed 40 h later. Liver microsomes were prepared and metabolites were formed by incubating rat liver microsomes or homogenized cells with /sup 3/H-labeled benzopyrene. Results indicated that the hydroxylase systems in the three species have different specificities for particular regions of the benzopyrene molecule. Metabolite profiles for benzopyrene were compared in hamster cells and mouse embryonic cells. (HLW)

Report Numbers

E 1.99:conf-7706119-2
conf-7706119-2

Subject(s)

Basic Biological Sciences

Other Subject(s)

Note

Published through SciTech Connect.
01/01/1977.
"conf-7706119-2"
6. Perugia international conference, Perugia, Italy, 30 Jun 1977.
Selkirk, J. K.; MacLeod, M. C.

Funding Information

W-7405-ENG-26

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