Mechanisms for radiation damage in DNA, Progress report, November 1, 1977--October 31, 1978. [Gamma radiation] [electronic resource].

Published:: Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 1978.
Physical Description:: Pages: 8 : digital, PDF file
Additional Creators:: United States. Department of Energy. Office of Scientific and Technical Information

Access Online

www.osti.gov

Availability

Finding items...

Restrictions on Access:

Free-to-read Unrestricted online access

Summary:

In this project we have proposed several mechanisms for radiation damage to DNA constituents and DNA, and have detailed a series of experiments utilizing electron spin resonance spectrometry to test the proposed mechanisms. In the past we have concentrated chiefly on the direct affect of radiation on DNA. We are currently investigating systems of DNA constituents and peptides which may shed light on indirect effects. Studies which we have completed during the past year are: ..pi..-cation radicals in DNA and dinucleoside phosphates, and conformational effects on the ESR Spectra of amino acids and peptides. Studies of ..gamma..-Irradiated Peptide Solutions at 77/sup 0/K, and studies of spin transfer in ..gamma..-irradiated nucleoside--peptide solutions were also conducted.

Report Numbers:

E 1.99:coo-2364-15
coo-2364-15

Subject(s):

Other Subject(s):

Note:

Published through SciTech Connect.
06/01/1978.
"coo-2364-15"
Sevilla, M.D.
Oakland Univ., Rochester, MI (USA)

Funding Information:

EY-76-S-02-2364

View MARC record | catkey: 13814801