This document describes the Cold Vacuum Drying Facility (CVDF) heating, ventilation, and air conditioning system (HVAC). The CVDF HVAC system consists of the Administrative building HVAC system, the process bay recirculation HVAC system, the process bay local HVAC and process vent system, the process general supply/exhaust HVAC system, and the Reference air system. These HVAC sub-systems support the CVDF process and provide secondary confinement of contamination and the required filtration of exhaust.