Asymmetric Intramolecular Alkylation of Chiral Aromatic Imines via Catalytic C-H Bond Activation [electronic resource].
- Published
- Berkeley, Calif. : Lawrence Berkeley National Laboratory, 2007.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy. - Additional Creators
- Lawrence Berkeley National Laboratory and United States. Department of Energy. Office of Scientific and Technical Information
Access Online
- Restrictions on Access
- Free-to-read Unrestricted online access
- Summary
- The asymmetric intramolecular alkylation of chiral aromatic aldimines, in which differentially substituted alkenes are tethered meta to the imine, was investigated. High enantioselectivities were obtained for imines prepared from aminoindane derivatives, which function as directing groups for the rhodium-catalyzed C-H bond activation. Initial demonstration of catalytic asymmetric intramolecular alkylation also was achieved by employing a sterically hindered achiral imine substrate and catalytic amounts of a chiral amine.
- Report Numbers
- E 1.99:lbnl-1510e
lbnl-1510e - Other Subject(s)
- Note
- Published through SciTech Connect.
04/16/2007.
"lbnl-1510e"
Synlett FT
Bergman, Robert; Ellman, Jonathan; Wilson, Rebecca; O'Malley, Steven; Watzke, Anja.
Chemical Sciences Division - Funding Information
- DE-AC02-05CH11231
View MARC record | catkey: 14392480