Advanced bioreactors for enhanced production of chemicals [electronic resource].

Published: Washington, D.C. : United States. Dept. of Energy, 1993.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy.
Physical Description: 10 pages : digital, PDF file
Additional Creators: Oak Ridge National Laboratory, United States. Department of Energy, and United States. Department of Energy. Office of Scientific and Technical Information

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Summary

A variety of advanced bioreactors are being developed to improve production of fuels, solvents, organic acids and other fermentation products. One key approach is immobilization of the biocatalyst leading to increased rates and yields. In addition, there are processes for simultaneous fermentation and separation to further increase production by the removal of an inhibitory product. For example, ethanol productivity in immobilized-cell fluidized-bed bioreactors (FBRs) can increase more than tenfold with 99% conversion and near stoichiometric yields. Two modified FBR configurations offer further improvements by removing the inhibitory product directly from the continuous fermentation. One involves the addition and removal of solid adsorbent particles to the FBR. This process was demonstrated with the production of lactic acid by immobilized Lactobacillus. The second uses an immiscible organic extractant in the FBR. This increased total butanol yields in the anaerobic acetone-butanol fermentation by Clostridium acetobutylicum.

Report Numbers

E 1.99:conf-930304--23
conf-930304--23

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Note

Published through SciTech Connect.
06/01/1993.
"conf-930304--23"
"DE93015451"
205. American Chemical Society national meeting,Denver, CO (United States),28 Mar - 2 Apr 1993.
Scott, C.D.; Davison, B.H.

Funding Information

AC05-84OR21400

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