Microdistribution of lead in bone [electronic resource] : A new approach
- Washington, D.C. : United States. Dept. of Energy, 1991.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy.
- Physical Description:
- Pages: (17 pages) : digital, PDF file
- Additional Creators:
- Brookhaven National Laboratory
United States. Department of Energy
United States. Department of Energy. Office of Scientific and Technical Information
- A knowledge of the microdistribution of lead in bone is important in order to understand the mechanisms for accumulation and release of lead. The availability of the synchrotron x-ray microscope for sensitive measurements of bone content and distribution of lead provides a valuable tool which, when combined with kinetic, balance, and tissue measurements, can lead to better evaluation of lead toxicity. It may also provide the basis for the development of a suitable model of how lead behaves in the human body. An outline of an experimental protocol for exploitation of the x-ray microscope is given, along with synchrotron x-ray microscope measurements of the distribution of gallium in rat bone that demonstrate the feasibility of the experimental approach.
- Published through SciTech Connect.
Workshop on lead: metabolism and bone deposition, Upton, NY (United States), 10-12 Apr 1991.
Jones, K.W.; Bronner, F.; Bockman, R.S. . Medical Coll.
- Funding Information:
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