In vivo monitoring of heavy metals in man [electronic resource] : cadmium and mercury

Published:: Upton, N.Y. : Brookhaven National Laboratory, 1982.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy.
Physical Description:: Pages: 5 : digital, PDF file
Additional Creators:: Brookhaven National Laboratory and United States. Department of Energy. Office of Scientific and Technical Information

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Summary:

Direct in vivo measurements of selected heavy metals is possible by nuclear analytical techniques. In particular, cadmium and mercury are retained in the body in sufficient quantities for their detection by neutron activation analysis. Autopsy data on cadmium of adult male non-smokers living in the US indicates an average body burden of 30 mg by age 50. The distribution of cadmium in the body, however, is nonuniform, approximately 50% being located in the kidneys and liver. The increased concentration of cadmium within these organs has made possible the direct in vivo measurements of this metal by prompt-gamma neutron activation analysis (PGNAA). At present, in vivo determinations of mercury have been performed on phantoms only. These in vivo techniques provide a unique method of obtaining accurate organ burden data in humans that can be related to the toxicological effects of these metals.

Report Numbers:

E 1.99:bnl-32243
E 1.99: conf-8210106-2
conf-8210106-2
bnl-32243

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Note:

Published through SciTech Connect.
01/01/1982.
"bnl-32243"
" conf-8210106-2"
"DE83005148"
Workshop on uses of nuclear analytical methods in metal toxicology, Upton, NY, USA, 11 Oct 1982.
Cohn, S.H.; Ellis, K.J.; Vartsky, D.

Funding Information:

AC02-76CH00016

View MARC record | catkey: 14397858