Biocompatible self-assembly of nano-materials for Bio-MEMS and insect reconnaissance [electronic resource].

Published: Washington, D.C. : United States. Dept. of Energy, 2003.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy.
Physical Description: 23 pages : digital, PDF file
Additional Creators: Sandia National Laboratories, United States. Department of Energy, and United States. Department of Energy. Office of Scientific and Technical Information

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Summary

This report summarizes the development of new biocompatible self-assembly procedures enabling the immobilization of genetically engineered cells in a compact, self-sustaining, remotely addressable sensor platform. We used evaporation induced self-assembly (EISA) to immobilize cells within periodic silica nanostructures, characterized by unimodal pore sizes and pore connectivity, that can be patterned using ink-jet printing or photo patterning. We constructed cell lines for the expression of fluorescent proteins and induced reporter protein expression in immobilized cells. We investigated the role of the abiotic/biotic interface during cell-mediated self-assembly of synthetic materials.

Report Numbers

E 1.99:sand2003-4075
sand2003-4075

Subject(s)

Materials Science

Other Subject(s)

Note

Published through SciTech Connect.
12/01/2003.
"sand2003-4075"
Brinker, C. Jeffrey; Sinclair, Michael B.; Calvert, Paul Davidson; Flemming, Jeb Hunter; Brozik, Susan Marie; Timlin, Jerilyn Ann; Werner-Washburne, Margaret C.; Manginell, Monica; Cesarano, Joseph, III; Dunphy, Darren Robert; Baca, Helen Kennicott; Ashley, Carlee E.; Hartenberger, Tamara N.

Funding Information

AC04-94AL85000

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