Actions for Modeling Single Molecule Fluorescence and Lasing. Final report [electronic resource].

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Modeling Single Molecule Fluorescence and Lasing. Final report [electronic resource].

Published
Washington, D.C. : United States. Dept. of Energy, 1998.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy.
Physical Description
4 pages : digital, PDF file
Additional Creators
United States. Department of Energy and United States. Department of Energy. Office of Scientific and Technical Information
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Summary
In FY 1998 our efforts were in three main areas, all related to detecting single fluorescent molecules [1] and understanding their emission. (1) We completed the calculations and analysis for a paper on spatial photoselection of single molecules on the surface of a dielectric microsphere. [2] Molecules that are oriented parallel to the surface of a spherical microcavity have position-dependent excitation probabilities and a collection efficiencies. The results are different for different polarizations. (2) We completed the modeling and analysis for a paper analyzing single molecule photocount statistics in microdroplets. [3] In this paper we employed a Monte Carlo technique to simulate effects of molecular occupancy, photobleaching, and fluorophor spatial diffusion within the droplet. We discussed the optimization of detection of single molecules in microdroplets. (3) We modeled the images of single molecules in microdroplets and submitted a preliminary report of these images in a paper which also showed experimental results. [4] The computed images depend upon the molecule's position within the microsphere, its orientation and emission frequency, and on the size and refractive index of the microsphere. For this work we used and modified models and computer codes developed previously, [5] as well as developed new models and codes.
Report Numbers
E 1.99:doe/or/22651--1-vol.1
doe/or/22651--1-vol.1
Subject(s)
Other Subject(s)
Note
Published through SciTech Connect.
10/01/1998.
"doe/or/22651--1-vol.1"
Hill, Steven C.
Army Research Laboratory, Adelphi, MD (US)
Type of Report and Period Covered Note
Final; 04/10/1998 - 10/01/1998
Funding Information
FG05-98OR22651
View MARC record | catkey: 14451557