Synthetic crude oils carcinogenicity screening tests. Progress report, February 15-September 15, 1979 [electronic resource].
- Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 1979.
- Physical Description:
- Pages: 34 : digital, PDF file
- Additional Creators:
- United States. Department of Energy. Office of Scientific and Technical Information
- Restrictions on Access:
- Free-to-read Unrestricted online access
- Four crude oils (Southern Louisiana Crude Petroleum, H Coal Syncrude, Paraho Crude Shale Oil and Geokinetics in situ Shale Oil) which were distilled into four fractions (naphtha, mid-distillate, gas oil and residue) for analysis and biological screening testing during the first report period were tested for mutagenicity by the Ames test and for tumor initiating activity by an initiation/promotion (skin painting) test. Substantial agreement exists between Ames and skin painting results. Low boiling fractions of the 4 crude oils showed little or no mutagenicity or tumor activity by the two tests used. The higher boiling fractions (mid gas oils and residues) and the crude oils themselves showed positive mutagenicity and tumor initiation activity. The coal derived fractions were more potent by both tests while the shale oil fractions showed greater activity than the petroleum fractions but considerably less than the coal syncrude.
- Published through SciTech Connect., 01/01/1979., "coo-4758-2", Calkins, W.H.; Deye, J.F.; King, C.F.; Hartgrove, R.W.; Krahn, D.F., and Du Pont de Nemours (E.I.) and Co., Wilmington, DE (USA)
- Funding Information:
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