Molecular Medicine [electronic resource] : Synthesis and In Vivo Detection of Agents for use in Boron Neutron Capture Therapy. Final Report
- Washington, D.C. : United States. Dept. of Energy. Office of Energy Research, 2005. and Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy.
- Physical Description:
- 31 pages : digital, PDF file
- Additional Creators:
- University of Tennessee (System). College of Medicine, United States. Department of Energy. Office of Energy Research, and United States. Department of Energy. Office of Scientific and Technical Information
- The primary objective of the project was the development of in vivo methods for the detection and evaluation of tumors in humans. The project was focused on utilizing positron emission tomography (PET) to monitor the distribution and pharamacokinetics of a current boron neutron capture therapy (BNCT) agent, p-boronophenylalanine (BPA) by labeling it with a fluorine-18, a positron emitting isotope. The PET data was then used to develop enhanced treatment planning protocols. The study also involved the synthesis of new tumor selective BNCTagents that could be labeled with radioactive nuclides for the in vivo detection of boron.
- Published through SciTech Connect., 06/28/2005., "doe/er/62189-5", and Kabalka, G. W.
- Type of Report and Period Covered Note:
- Final; 05/01/1999 - 04/30/2003
- Funding Information:
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