Synthesis of tracers using automated radiochemistry and robotics [electronic resource].
- Washington, D.C. : United States. Dept. of Energy, 1992.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy.
- Physical Description:
- Pages: (4 pages) : digital, PDF file
- Additional Creators:
- Johns Hopkins University
United States. Department of Energy
United States. Department of Energy. Office of Scientific and Technical Information
- Synthesis of high specific activity radiotracers labeled with short-lived positron-emitting radionuclides for positron emission tomography (PET) often requires handling large initial quantities of radioactivity. High specific activities are required when preparing tracers for use in PET studies of neuroreceptors. A fully automated approach for tracer synthesis is highly desirable. This proposal involves the development of a system for the Synthesis of Tracers using Automated Radiochemistry and Robotics (STARR) for this purpose. While the long range objective of the proposed research is the development of a totally automated radiochemistry system for the production of major high specific activity ¹¹C-radiotracers for use in PET, the specific short range objectives are the automation of ¹¹C-methyl iodide (¹¹CH₃I) production via an integrated approach using both radiochemistry modular labstations and robotics, and the extension of this automated capability to the production of several radiotracers for PET (initially, ¹¹C-methionine, 3-N-(¹¹C-methyl)spiperone, and (¹¹C)-carfentanil).
- Published through SciTech Connect.
- Funding Information:
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