Traversal of cells by radiation and absorbed fraction estimates for electrons and alpha particles [electronic resource].

Published:: Oak Ridge, Tenn. : Oak Ridge National Laboratory, 1985.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy.
Physical Description:: Pages: 17 : digital, PDF file
Additional Creators:: Oak Ridge National Laboratory and United States. Department of Energy. Office of Scientific and Technical Information

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Summary:

Consideration of the pathlength which radiation traverses in a cell is central to algorithms for estimating energy deposition on a cellular level. Distinct pathlength distributions occur for radionuclides: (1) uniformly distributed in space about the cell (referred to as -randomness); (2) uniformly distributed on the surface of the cell (S-randomness); and (3) uniformly distributed within the cell volume (I-randomness). For a spherical cell of diameter d, the mean pathlengths are 2/3d, 1/2d, and 3/4d, respectively, for these distributions. Algorithms for simulating the path of radiation through a cell are presented and the absorbed fraction in the cell and its nucleus are tabulated for low energy electrons and alpha particles emitted on the surface of spherical cells. The algorithms and absorbed fraction data should be of interest to those concerned with the dosimetry of radionuclide-labeled monoclonal antibodies. 8 refs., 3 figs., 2 tabs.

Report Numbers:

E 1.99:conf-851113-4
conf-851113-4

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Note:

Published through SciTech Connect.
01/01/1985.
"conf-851113-4"
"DE86006095"
Radiopharmaceutical dosimetry symposium, Oak Ridge, TN, USA, 5 Nov 1985.
Kerr, G.D.; Eckerman, K.F.; Ryman, J.C.; Taner, A.C.

Funding Information:

AC05-84OR21400

View MARC record | catkey: 14793903