Actions for Microdosimetry for Boron Neutron Capture Therapy [electronic resource].

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Microdosimetry for Boron Neutron Capture Therapy [electronic resource].

Published
Washington, D.C. : United States. Dept. of Energy. Office of Energy Research, 2000.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy.
Physical Description
5 pages : digital, PDF file
Additional Creators
United States. Department of Energy. Office of Energy Research and United States. Department of Energy. Office of Scientific and Technical Information
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Summary
The specific aims of the research proposal were as follows: (1) To design and construct small volume tissue equivalent proportional counters for the dosimetry and microdosimetry of high intensity thermal and epithermal neutron beams used in BNCT, and of modified fast neutron beams designed for boron neutron capture enhanced fast neutron therapy (BNCEFNT). (2) To develop analytical methods for estimating the biological effectiveness of the absorbed dose in BNCT and BNCEFNT based on the measured microdosimetric spectra. (3) To develop an analytical framework for comparing the biological effectiveness of different epithermal neutron beams used in BNCT and BNCEFNT, based on correlated sets of measured microdosimetric spectra and radiobiological data. Specific aims (1) and (2) were achieved in their entirety and are comprehensively documented in Jay Burmeister's Ph.D. dissertation entitled ''Specification of physical and biologically effective absorbed dose in radiation therapies utilizing the boron neutron capture reaction'' (Wayne State University, 1999). Specific aim (3) proved difficult to accomplish because of a lack of sufficient radiobiological data.
Report Numbers
E 1.99:770637
Subject(s)
Other Subject(s)
Note
Published through SciTech Connect.
09/05/2000.
Maughan, R.L.; Kota, C.
Wayne State Univ., Detroit, MI (US)
Type of Report and Period Covered Note
Final; 08/01/1996 - 07/31/2000
Funding Information
FG02-96ER62217
View MARC record | catkey: 14794689