Actions for Attomole detection of isotope-labeled compounds in chemical defense research [electronic resource].

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Attomole detection of isotope-labeled compounds in chemical defense research [electronic resource].

Published
Washington, D.C. : United States. Dept. of Energy, 1996.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy.
Physical Description
11 pages : digital, PDF file
Additional Creators
Lawrence Livermore National Laboratory, United States. Department of Energy, and United States. Department of Energy. Office of Scientific and Technical Information
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Summary
AMS detects 14C at zeptomole to femtomole sensitivities. We detected the effect of ChE-blocking pyridostigmine bromide on the CNS uptake of a pyrethroid insecticide at scaled human-equivalent exposures in rats. Significant blood to brain protection from permethrin dosed at 5mg/kg is seen in the CNS of rats receiving pyridostigmine bromide pretreatments in chow at 2mg/kg/day. The synergy of these compounds was suggested as a precursor to some symptoms of `Gulf War Syndrome`.
Report Numbers
E 1.99:ucrl-jc--125921
E 1.99: conf-961191--4
conf-961191--4
ucrl-jc--125921
Subject(s)
Other Subject(s)
Note
Published through SciTech Connect.
11/01/1996.
"ucrl-jc--125921"
" conf-961191--4"
"DE97053397"
1996 Edgewood Research, Development and Engineering Center (RDEC) scientific conference on obscuration and aerosol research, Aberdeen, MD (United States), 19-22 Nov 1996.
Vogel, J.S.; Turteltaub, K.; Buchholz, B.A.; Dingley, K.; Mauthe, R.E.; Pawley, N.H.
Funding Information
W-7405-ENG-48
View MARC record | catkey: 14796489