Actions for Using Concurrent Cardiovascular Information to Augment Survival Time Data from Orthostatic Tilt Tests

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Using Concurrent Cardiovascular Information to Augment Survival Time Data from Orthostatic Tilt Tests

Author
Platts, Steven H.
Published
August 2, 2014.
Physical Description
1 electronic document
Additional Creators
Fiedler, James, Lee, Stuart M. M., Stenger, Michael B., Feiveson, Alan H., and Westby, Christian M.
Online Version

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Unclassified, Unlimited, Publicly available.
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Summary
Orthostatic Intolerance (OI) is the propensity to develop symptoms of fainting during upright standing. OI is associated with changes in heart rate, blood pressure and other measures of cardiac function. Problem: NASA astronauts have shown increased susceptibility to OI on return from space missions. Current methods for counteracting OI in astronauts include fluid loading and the use of compression garments. Multivariate trajectory spread is greater as OI increases. Pairwise comparisons at the same time within subjects allows incorporation of pass/fail outcomes. Path length, convex hull area, and covariance matrix determinant do well as statistics to summarize this spread Missing data problems Time series analysis need many more time points per OTT session treatment of trend? how incorporate survival information?
Other Subject(s)
Collection
NASA Technical Reports Server (NTRS) Collection.
Note
Document ID: 20140009929.
JSC-CN-31445.
Joint Statistical Meetings 2014; 2-7 Aug. 2014; Boston, MA; United States.
Terms of Use and Reproduction
Copyright, Distribution as joint owner in the copyright.
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