[Effects of Gravity on Attachment of Tendon to Bone].
- Johnson, Roger B.
- Physical Description:
- 1 electronic document
- Restrictions on Access:
- Unclassified, Unlimited, Publicly available.
- We have received and processed all samples for either light or scanning electron microscopic analysis and have completed the histomorphometric analysis. We have characterized the changes caused by spaceflight to tendon attachments to the calcaneus, tibia, fibula and femur and compared them to hindlimbs and forelimbs from NIH.RZ. Soleus muscle histomorphometry has also been completed. Our results suggest severe osteoporosis in the femur, fibula and tibia of animals coincident to spaceflight, which had not resolved after 4-5 days following return to earth. This was evident at all sites, including sites of tendon attachments. This atrophy was not evident in the calcaneus. No muscle atrophy was evident. Comparison of scanning photomicrographs of flight animals with other lactating animals demonstrated structural similarities and suggested that it might be worthwhile to assess whether lactation is a factor in development of the osteoporosis in the spaceflight animals. In addition, evaluation of total calcium utilization by spaceflight animals would be beneficial.
- Document ID: 19980007217.
- No Copyright.
View MARC record | catkey: 15646654