Actions for Experiment K-6-13. Morphological and biochemical examination of heart tissue. Part 1 : Effects of microgravity on the myocardial fine structure of rats flown on Cosmos 1887. Ultrastructure studies. Part 2: Cellular distribution of cyclic ampdependent protein kinase regulatory subunits in heart muscle of rats flown on Cosmos 1887

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Experiment K-6-13. Morphological and biochemical examination of heart tissue. Part 1 : Effects of microgravity on the myocardial fine structure of rats flown on Cosmos 1887. Ultrastructure studies. Part 2: Cellular distribution of cyclic ampdependent protein kinase regulatory subunits in heart muscle of rats flown on Cosmos 1887

Author
Popova, I. A.
Published
Feb 1, 1990.
Physical Description
1 electronic document
Additional Creators
Kato, K., Mednieks, M. I., Philpott, D. E., Sapp, W., Stevenson, J., Miquel, Jaime, and Serova, L. V.
Online Version

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Summary
The left ventricle of hearts from rats flown on the Cosmos 1887 biosatellite for 12.5 days was compared to the same tissue of synchronous and vivarium control animals maintained in a ground based laboratory. The volume density of the mitochondria in the myocardium of the space-flown animals was statistically less (p equal less than 0.01) than that of the synchronous or vivarium control rats. Exposure to microgravity resulted in a certain degree of myocardial degeneration manifested in mitochondrial changes and accumulation of myeloid bodies. Generalized myofibrillar edema was also observed.
Other Subject(s)
Collection
NASA Technical Reports Server (NTRS) Collection.
Note
Document ID: 19900017151.
Accession ID: 90N26467.
The US Experiments Flown on the Soviet Biosatellite Cosmos 1887; p 297-329.
Terms of Use and Reproduction
No Copyright.
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