Experimental gastric ulcers induced by immobilization and electric shock of rats and their pharmacotherapy
- Zabrodin, O. N.
- May 1, 1980.
- Physical Description:
- 1 electronic document
- Restrictions on Access:
- Unclassified, Unlimited, Publicly available. and Free-to-read Unrestricted online access
- The mechanism of development of experimental gastric ulcers, induced in rats by combined immobilization and electric shock, was analyzed pharmacologically with peripheral neurotropic agents. It is concluded that: (1) The most marked preventive effect in the development of the experimentally induced gastric ulcers was displayed by agents capable of blocking the ascending activation system of the reticular formation. (2) Sympathetic fibers, which disrupt the trophism of the gastric wall, form the efferent portion of the reflex arc. (3) Gastric secretion does not appear to be the primary cause of ulceration.
- NASA Technical Reports Server (NTRS) Collection.
- Document ID: 19800019480., Accession ID: 80N27981., and NASA-TM-76157.
- No Copyright.
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