Immune System Dysregulation and Herpesvirus Reactivation Persist During Long-Duration Spaceflight

Author:: Uchakin, P.
Published:: April 11, 2011.
Physical Description:: 1 electronic document
Additional Creators:: Sams, C. F., Stowe, R. P., Mehta, S., Crucian, B. E., Pierson, D., and Quiriarte, H.

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Summary:

This poster presentation reviews a study that is designed to address immune system dysregulation and the risk to crewmembers in long duration exploration class missions. This study will address these objectives: (1) Determine the status of adaptive immunity physiological stress, viral immunity, latent herpesvirus reactivation in astronauts during 6 month missions to the International Space Station; (2) determine the clinical risk related to immune dysregulation for exploration class spaceflight; and (3) determine an appropriate monitoring strategy for spaceflight-associated immune dysfunction that could be used for the evaluation of countermeasures. The study anticipates 17 subjects, and for this presentation, (midpoint study data) 10 subjects are reviewed.

Other Subject(s):

Aerospace Medicine

Collection:

NASA Technical Reports Server (NTRS) Collection.

Note:

Document ID: 20110008227.
JSC-CN-23143.
18th IAA Humans in Space Symposium; 11-15 Apr. 2011; Houston, TX; United States.

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