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Advances in clinical chemistry. Volume sixty-seven / edited by Gregory S. Makowski, Clinical Laboratory Partners Newington, CT.

Published
Amsterdam, Netherlands : Academic Press, 2014.
Copyright Date
©2014
Edition
First edition.
Physical Description
1 online resource (285 pages) : illustrations
Additional Creators
Makowski, Gregory S. (Gregory Stephen)
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Contents
Cover image; Title page; Table of Contents; Copyright; Contributors; Preface; Chapter One: Biomarkers of Tobacco Smoke Exposure; Abstract; 1 Introduction; 2 Definitions; 3 Types of Biomarkers; 4 Biomarkers of Smoking Versus Biomarkers of Biological State; 5 From Smoke to Disease: Genomics and Novel Molecular Pathways; 6 Modulating Factors; 7 Biomarker Uses; 8 Validation and Qualification; 9 Conclusions; Disclaimer; Chapter Two: Ethyl Glucuronide and Ethyl Sulfate; Abstract; 1 Introduction; 2 Metabolism of Alcohol; 3 Stability; 4 Cutoff Values; 5 Detection Times, 6 Methods for Measurement of EtG and EtS7 Applications; 8 Confounders Causing False-Positive or False-Negative Results; 9 Conclusions; Declarations; Chapter Three: Ammonia Metabolism and Hyperammonemic Disorders; Abstract; 1 Introduction; 2 Solubility of Ammonia and Transport Across Cell Membranes; 3 Sources of Ammonia; 4 Disposal of Ammonia; 5 Ammonia Metabolism in Liver; 6 Ammonia Metabolism in Brain; 7 Ammonia and Arginine Production in the Kidneys; 8 Toxicity of Ammonia; 9 The Pathogenesis of Hyperammonemic Encephalopathy; 10 Clinical Disorders with HA: Overview, 11 Inherited Hyperammonemic Disorders12 Liver Disease; 13 Sodium Valproate; 14 Urinary Tract Disorders; 15 Miscellaneous Causes; 16 Conclusions; Chapter Four: 5-Methylcytosine and Its Derivatives; Abstract; 1 Introduction; 2 Global Detection of 5-mC and Its Oxidation Derivatives; 3 Location Analysis of 5-mC and Its Derivatives; 4 Conclusions and Perspectives; Acknowledgments; Chapter Five: Circulating microRNAs as Promising Tumor Biomarkers; Abstract; 1 Introduction; 2 miRNA Biogenesis; 3 miRNAs and Cancer; 4 Origin and Function of Circulating miRNAs; 5 Detection of Circulating miRNAs, 6 Circulating miRNAs as Cancer Biomarkers7 Conclusions; Chapter Six: Proteomics in Transplantation; Abstract; 1 Introduction; 2 History; 3 Sample Sources; 4 Proteomic Technology; 5 Proteomic Studies; 6 Future Aspects, Quo Vadis?; Chapter Seven: Fibulins and Their Role in Cardiovascular Biology and Disease; Abstract; 1 Introduction; 2 Genes, Expression and Biochemistry; 3 Genetically Modified Animals; 4 Expression of Fibulins in Heart and Vasculature During Development; 5 Fibulins in Arterial Disease; 6 Fibulins and Heart Disease; 7 Circulating Fibulins; 8 Fibulins and Hemostasis, and 9 Fibulins and Possible Mechanism of Regulation10 Conclusions and Perspectives; Index
Summary
Volume 67 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of Clinical Chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Expertise of international contributors
  • Latest cutting-edge technologies
  • Comprehensive in scope
Subject(s)
Genre(s)
ISBN
9780128022672
9780128024669 (e-book)
0128024666 (e-book)
9780128022665
0128022663
Bibliography Note
Includes bibliographical references at the end of each chapters and index.
View MARC record | catkey: 16832382