Lysophospholipids and eicosanoids in biology and pathophysiology / edited by Edward J. Goetzl and Kevin R. Lynch

Published:: New York, N.Y. : New York Academy of Sciences, 2000.
Physical Description:: xiv, 357 pages : illustrations ; 24 cm.
Additional Creators:: Goetzl, Edward J. and Lynch, Kevin R.

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Series:

Annals of the New York Academy of Sciences ; v. 905

Contents:

Preface: the omnific lysphospholipid growth factors -- Development of our current understanding of bioactive lysophospholipids -- Group IV cytosolic phospholipase A₂ activation by diacylglycerol pyrophosphate in murine P388D*¹ macrophages -- Sphingosine-1-phosphate signaling via the EDG-1 family of G-protein-coupled receptors -- Molecular identification and characterization fo G-protein-coupled receptors for lysophosphatidic acid and sphingosine 1-phosphate -- Pharmacological characterization of phospholipid growth-factor receptors -- Sphingosine 1-phosphate: a ligand for the EDG-1 family of G-protein-coupled receptors -- Phospholipase D -- A novel polyisoprenyl phosphate signaling cascade in human neutrophils -- Lipid phosphate phosphatase-1 in the regulation of lysophosphatidate signaling -- The role of De Novo ceramide synthesis in chemotherapy-induced apoptosis -- PPAR-γ-mediated regulation of normal and malignant B lineage cells -- Neurobiology of receptor-mediated lysophospholipid signaling: from the first lysophosepholipid receptor to roles in nervous system fuctin and development -- EDG receptors as a therapeutic target in the nervous system -- Lysophosphatidic acid induction of neuronal apoptosis and necrosis -- Phospholipid growth factors and corneal wound healing -- LPA as a paracrine mediator of adipocyte growth and function --- Eicosanoid regulation of angiogenesis in human prostate carcinoma and its therapeutic implications -- Mechanisms of lysolipid phosphate effects on cellular survival and proliferation -- Lysophospholipid growth factors in the initiation progression, metastases and management of ovarian cancer -- Sphingolipid regulation of female gonadal cell apoptosis -- Structure-function analyses of eicosanoid receptors: physiologic and therapeutic implications -- The molecular pharmacology of lysophosphatidate signaling -- Evaluation of plasma-lysophospholipids for diagnostic significance using electrospray ionizatin mass spectrometry (ESI-MS) analyses -- Poster papers.

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ISBN:

1573312134 (cloth : alk. paper)
1573312142 (paper : alk. paper)

Bibliography Note:

Includes bibliographical references and index.

View MARC record | catkey: 2029814