Actions for Nanotechnology methods for neurological diseases and brain tumors : drug delivery across the blood--brain barrier
Nanotechnology methods for neurological diseases and brain tumors : drug delivery across the blood--brain barrier / Yasemin Gürsoy-Özdemir, Sibel Bozdağ-Pehlivan, Emine Sekerdag
- Author
- Gürsoy-Özdemir, Yasemin
- Published
- London : Academic Press, [2017]
- Copyright Date
- ©2017
- Physical Description
- 1 online resource
- Additional Creators
- Bozdağ-Pehlivan, Sibel and Sekerdag, Emine
Access Online
- Contents
- Machine generated contents note: pt. 1 The Rationale to Reach the Brain -- ch. 1 Anatomy and Physiology of the Blood--Brain Barrier / Yagmur Cetin Tas -- 1.Introduction -- 2.Structure of the BBB -- 3.BBB Developmental Steps -- 4.Transport Across the BBB -- 5.Conclusions -- Abbreviations -- References -- ch. 2 Blood--Brain Barrier: Genomics, Proteomics, Disease Targets, and Drug Delivery / Ayse Filiz Oner -- 1.Introduction -- 2.Blood--Brain Barrier Genomics -- 3.Blood--Brain Barrier Proteomics -- 4.Disease Targets -- 5.Drug Delivery -- 6.Conclusions -- Abbreviations -- References -- ch. 3 Brain and the Drug Transporters / Selma Sahin -- 1.Introduction -- 2.Brain Transporters -- 3.Conclusions -- Abbreviations -- References -- ch. 4 Drug Delivery to the Brain: Pharmacokinetic Concepts / Levent Oner -- 1.Introduction -- 2.CNS Drug Delivery -- 3.Intrabrain Distribution -- 4.Conclusions -- Abbreviations -- References -- pt. 2 Nose-to-Brain Drug Delivery -- ch. 5 Nasal Physiology and Drug Transport / Emine Sekerdag -- 1.Introduction -- 2.Anatomy of the Nose -- 3.Nasal Transport Mechanisms -- 4.Factors Affecting Nose-to-Brain Transport -- 5.Principles of Drug Administration -- 6.Conclusions -- Abbreviations -- References -- ch. 6 Challenges of the Nose-to-Brain Route / Emine Sekerdag -- 1.Introduction -- 2.Nose-to-Brain Research -- 3.Overcoming Barriers in Nasal Drug Delivery -- 4.In Vitro and In Vivo Models for Nasal Drug Delivery -- 5.Conclusions -- Abbreviations -- References -- pt. 3 Nanoscience in Targeted Brain Drug Delivery -- ch. 7 Nanoscience in Targeted Brain Drug Delivery / Sibel Bozdag-Pehlivan -- 1.Importance and Application of Nanotechnology-Based Brain Drug Delivery Systems -- 2.Neurotoxicity -- 3.Clinical Considerations -- 4.Ethical and Regulatory Issues -- 5.Conclusions -- Abbreviations -- References -- pt. 4 Brain-Targeted Experimental Models -- ch. 8 In Vitro CNS Models / Imran Vural -- 1.Introduction -- 2.Cellular Structure of the BBB -- 3.Tight Junctions and In Vitro Paracellular Barrier Characterization -- 4.Cell Culture Models -- 5.Comparison of In Vitro Cell Culture Models -- 6.Conclusions and Future Outlook -- Abbreviations -- References -- ch. 9 In Vivo/In Situ Animal Models / Muhammed Abdur Rauf -- 1.Introduction -- 2.Animal Models of Alzheimer's Disease -- 3.Animal Models of Parkinson's Disease -- 4.Animal Models of Huntington's Disease -- 5.Animal Models of Depression -- 6.Animal Models of Anxiety -- 7.Animal Models of Schizophrenia -- 8.Animal Models of Pain -- 9.Animal Models of Stroke -- 10.Animal Models of Brain Tumor -- 11.Conclusions -- Abbreviations -- References -- ch. 10 Microdialysis and Brain Perfusion / Margareta Hammarlund-Udenaes -- 1.Introduction -- 2.Techniques in Relation to Measured Entities -- 3.Microdialysis -- 4.Open Flow Microperfusion -- 5.In Situ Brain Perfusion -- 6.Discussion -- Abbreviations -- References -- ch. 11 Neuroimaging: Techniques and General Applications / Kader Karli Oguz -- 1.Introduction -- 2.Ultrasonography -- 3.Computed Tomography -- 4.Magnetic Resonance Imaging -- 5.Positron Emission Tomography -- 6.Conclusions -- Abbreviations -- References -- pt. 5 Targeted Treatment Strategies for Neurological Diseases -- ch. 12 Alzheimer / Chi Zhang -- 1.Introduction -- 2.Strategies for Brain Drug Delivery in AD Treatment -- 3.Future Perspectives -- Abbreviations -- References -- ch. 13 Parkinson's Disease / Gul Yalcin Cakmakli -- 1.Introduction -- 2.Clinical Features -- 3.Etiology and Pathogenesis -- 4.Neuroanatomy of the Basal Ganglia -- 5.Treatment of Parkinson's Disease -- 6.Targeted Treatment Strategies for Parkinson's Disease -- 7.Conclusions -- Abbreviations -- References -- ch. 14 Stroke / Yasemin Gursoy-Ozdemir -- 1.Introduction -- 2.Current Treatment Strategies -- 3.Saving Penumbral Tissue -- 4.Neuroprotective Strategies -- 5.Imaging Techniques -- 6.Conclusions -- Abbreviations -- References -- ch. 15 Nanotechnology-Based Management of Neurological Autoimmune Diseases / Erdem Tuzun -- 1.General Concepts -- 2.A Useful Model for Nanoparticle Experiments on CNS Autoimmunity -- 3.Imaging of Inflammatory Nervous System Disorders by Nanoparticles -- 4.Nanotechnology in the Treatment of Autoimmune Neurological Disorders -- 5.Administration of Antiinflammatory Agents -- 6.Tolerance Induction -- 7.Neuroprotection -- 8.Nanotechnology in Nonautoimmune Neuroinflammation -- 9.Neuroinflammatory Adverse Effects of Nanoparticles -- 10.Concluding Remarks -- Abbreviations -- References -- ch. 16 Infectious Diseases of the Brain / Melike Ekizoglu -- 1.Introduction -- 2.Brain Infections -- 3.Consideration of the Treatment of Brain Infections -- 4.Nanotechnological Approach and Recent Trends in Brain Infection Treatments -- 5.Conclusions -- Abbreviations -- References -- pt. 6 Brain Tumors -- ch. 17 Brain Tumors / Sibel Bozdag-Pehlivan -- 1.Introduction -- 2.Types of Brain Tumors -- 3.Conventional Treatment Approaches -- 4.Blood--Brain Tumor Barrier -- 5.Overcoming the BBB -- 6.Nanotechnology-Based Drug Delivery Systems -- 7.Dual Therapies and Clinical Studies -- 8.Conclusions -- Abbreviations -- References.
- Subject(s)
- ISBN
- 9780128038000 (electronic bk.)
0128038004 (electronic bk.)
9780128037966 - Bibliography Note
- Includes bibliographical references and index.
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