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Advances in genetics. Volume 97 [electronic resource] / editors, Theodore Friedman, Jay C. Dunlap, Stephen F. Goodwin

Published
[Place of publication not identified] : Academic Press, 2017.
Physical Description
1 online resource
Additional Creators
Friedmann, Theodore, Dunlap, Jay C., and Goodwin, Stephen F.
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Contents
Front Cover; Advances in Genetics; ADVANCES IN GENETICS, VOLUME 97; Advances in GeneticsEdited byTheodore FriedmannDepartment of Pediatrics, University of California at San Diego,School of Me ...; Advances in GeneticsEdited byTheodore FriedmannDepartment of Pediatrics, University of California at San Diego,School of Me ...; Contents; CONTRIBUTORS; One -- Sixteen Years of Meiotic Silencing by Unpaired DNA; 1. INTRODUCTION; 2. THE DISCOVERY OF MEIOTIC SILENCING BY UNPAIRED DNA; 2.1 Asm-1, a Conserved Regulator of Fungal Development; 2.2 Mating in Neurospora crassa, 2.3 Ascus Dominance and Gene Pairing During Meiosis2.4 Meiotic Silencing by Unpaired DNA; 3. GENETIC ANALYSIS OF THE UNPAIRED DNA DETECTION MECHANISM OF MEIOTIC SILENCING BY UNPAIRED DNA; 3.1 Properties of Unpaired DNA Required for Silencing; 3.2 Meiotic Silencing by Unpaired DNA Silencing Does Not Spread Between Asci or Genes; 3.3 DNA Methylation Interferes With the Identification of Pairing Partners; 3.4 The Search for Pairing Partners Is Spatially Constrained; 4. RNA SILENCING AND MEIOTIC SILENCING BY UNPAIRED DNA PROTEINS; 4.1 Silencing the Silencer, 4.2 Meiotic Silencing by Unpaired DNA Is a Small RNA-Based Silencing Pathway4.3 Identification and Characterization of Other Meiotic Silencing by Unpaired DNA Proteins; 4.4 A Silencing Complex Stands Guard Around the Nucleus During Meiosis; 4.5 A Model for Meiotic Silencing by Unpaired DNA; 5. MEIOTIC SILENCING BY UNPAIRED DNA IN THE WILD; 6. THE PURPOSE OF MEIOTIC SILENCING BY UNPAIRED DNA; 7. CONCLUSION; REFERENCES; Two -- Sleeping Beauty? Developmental Timing, Sleep, and the Circadian Clock in Caenorhabditis elegans; 1. INTRODUCTION, 2. CIRCADIAN CLOCKS AND THE CAENORHABDITIS ELEGANS DEVELOPMENTAL TIMER2.1 Postembryonic Development in Caenorhabditis elegans; 2.2 How Does a Biological Clock Look?; 2.3 The Mechanism of the Circadian Clock; 2.4 A Clock Gene Homolog and Its Role in Postembryonic Development; 2.5 New Methods to Study Larval Development in Single Animals; 3. SLEEP; 3.1 Caenorhabditis elegans Sleeplike Behavior; 3.2 Neural Activity During Caenorhabditis elegans Lethargus; 3.3 Neuromodulators and Molecular Pathways Regulating Caenorhabditis elegans Lethargus; 4. SYNTHESIS, and 4.1 Using Lethargus to Learn About Sleep (and Vice Versa)4.1.1 Applying the Two-Process Model to Worms; 4.1.2 Linking the Function of Sleep to Mechanisms; 4.1.3 On the Level of Circuits and Molecules; 4.2 Using the Circadian Clock to Learn About Developmental Timing (and Vice Versa); 4.2.1 What Is the Same and What Is Different?; 4.2.2 The Molecular Mechanism of Biological Oscillators; 4.2.3 Outputs of Oscillators; 4.2.4 Iterating Between Models; ACKNOWLEDGMENTS; REFERENCES; Three -- Integrated Genomic Medicine: A Paradigm for Rare Diseases and Beyond; 1. INTRODUCTION; 1.1 Stratified Medicine
Subject(s)
ISBN
9780128122259 (electronic bk.)
0128122250 (electronic bk.)
9780128122242
0128122242
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