Sequential self-assembly of DNA functionalized droplets [electronic resource].
- Washington, D.C. : United States. Dept. of Energy. Office of Science, 2017.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy
- Physical Description:
- Article numbers 21 : digital, PDF file
- Additional Creators:
- New York University
United States. Department of Energy. Office of Science
United States. Department of Energy. Office of Scientific and Technical Information
- Complex structures and devices, both natural and manmade, are often constructed sequentially. From crystallization to embryogenesis, a nucleus or seed is formed and built upon. Sequential assembly allows for initiation, signaling, and logical programming, which are necessary for making enclosed, hierarchical structures. Though biology relies on such schemes, they have not been available in materials science. We demonstrate programmed sequential self-assembly of DNA functionalized emulsions. The droplets are initially inert because the grafted DNA strands are pre-hybridized in pairs. Active strands on initiator droplets then displace one of the paired strands and thus release its complement, which in turn activates the next droplet in the sequence, akin to living polymerization. This strategy provides time and logic control during the self-assembly process, and offers a new perspective on the synthesis of materials.
- Published through SciTech Connect.
Nature Communications 8 1 ISSN 2041-1723 AM
Yin Zhang; Angus McMullen; Lea-Laetitia Pontani; Xiaojin He; Ruojie Sha; Nadrian C. Seeman; Jasna Brujic; Paul M. Chaikin.
- Funding Information:
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