Microorganisms for producing organic acids [electronic resource].
- Published:
- Washington, D.C. : United States. Dept. of Energy, 2014.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy - Additional Creators:
- United States. Department of Energy
United States. Department of Energy. Office of Scientific and Technical Information - Access Online:
- www.osti.gov
- Summary:
- Organic acid-producing microorganisms and methods of using same. The organic acid-producing microorganisms comprise modifications that reduce or ablate AcsA activity or AcsA homolog activity. The modifications increase tolerance of the microorganisms to such organic acids as 3-hydroxypropionic acid, acrylic acid, propionic acid, lactic acid, and others. Further modifications to the microorganisms increase production of such organic acids as 3-hydroxypropionic acid, lactate, and others. Methods of producing such organic acids as 3-hydroxypropionic acid, lactate, and others with the modified microorganisms are provided. Methods of using acsA or homologs thereof as counter-selectable markers are also provided.
- Subject(s):
- Note:
- Published through SciTech Connect.
09/30/2014.
"8,846,354"
"14/200,747"
Pfleger, Brian; Begemann, Matthew.
Wisconsin Alumni Research Foundation, Madison, WI (United States) - Funding Information:
- FC02-07ER64494
View MARC record | catkey: 23493064