Methods for improved selectivity in photo-activation and detection of molecular diagnostic agents [electronic resource].
- Published
- Washington, D.C. : United States. Dept. of Energy, 2008.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy - Additional Creators
- United States. Department of Energy and United States. Department of Energy. Office of Scientific and Technical Information
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- Restrictions on Access
- Free-to-read Unrestricted online access
- Summary
- A method for the imaging of a particular volume of plant or animal tissue, wherein the plant or animal tissue contains at least one photo-active molecular agent. The method comprises the steps of treating the particular volume of the plant or animal tissue with light sufficient to promote a simultaneous two-photon excitation of the photo-active molecular agent contained in the particular volume of the plant or animal tissue, photo-activating at least one of the at least one photo-active molecular agent in the particular volume of the plant or animal tissue, thereby producing at least one photo-activated molecular agent, wherein the at least one photo-activated molecular agent emits energy, detecting the energy emitted by the at least one photo-activated molecular agent, and producing a detected energy signal which is characteristic of the particular volume of plant or animal tissue. The present invention also provides a method for the imaging of a particular volume of material, wherein the material contains at least one photo-active molecular agent.
- Report Numbers
- E 1.99:7,346,387
7,346,387 - Subject(s)
- Note
- Published through SciTech Connect.
03/18/2008.
"7,346,387"
"US patent application 09/072,963"
Wachter, Eric A. (Oak Ridge, TN); Fisher, Walter G. (Knoxville, TN); Dees, H. Craig (Knoxville, TN).
Lockheed Martin Energy Systems, Inc. - Funding Information
- AC05-84OR21400
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