<i>In-situ</i> photopolymerization of monodisperse and discoid oxidized methacrylated alginate microgels in a microfluidic channel [electronic resource].
- Washington, D.C. : United States. Dept. of Energy. Office of Science, 2016. and Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy
- Physical Description:
- Article numbers 011,101 : digital, PDF file
- Additional Creators:
- Oak Ridge National Laboratory, United States. Department of Energy. Office of Science, and United States. Department of Energy. Office of Scientific and Technical Information
- Restrictions on Access:
- Free-to-read Unrestricted online access
- Here, we present a simple microfluidic technique to <i>in-situ</i> photopolymerize (by 365 nm ultraviolet) monodisperse oxidized methacrylated alginate (OMA) microgels using a photoinitiator (VA-086). By this technique, we generated monodisperse spherical OMA beads and discoid non-spherical beads with better shape consistency than ionic crosslinking methods do. We found that a high monomer concentration (8 w/v %), a high photoinitiator concentration (1.5 w/v %) and absence of oxygen are critical factors to cure OMA microgels. This photopolymerizing method is an alternative to current methods to form alginate microgels and is a simpler approach to generate non-spherical alginate microgels.
- Published through SciTech Connect., 02/03/2016., "KC0403040", "ERKCZ01", Biomicrofluidics 10 1 ISSN 1932-1058; BIOMGB AM, and Shuo Wang; Oju Jeon; Peter G. Shankles; Yuan Liu; Eben Alsberg; Scott T. Retterer; Bruce P. Lee; Chang Kyoung Choi.
- Funding Information:
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