Actions for Arrays of probes for positional sequencing by hybridization [electronic resource].

Email RIS file
Bookmark
Report an Issue

Arrays of probes for positional sequencing by hybridization [electronic resource].

Published
Washington, D.C. : United States. Dept. of Energy, 2008.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy
Additional Creators
United States. Department of Energy. Office of Management, United States. Department of Energy, and United States. Department of Energy. Office of Scientific and Technical Information
Access Online

Availability

I Want It
I Want It

Finding items...

Restrictions on Access
Free-to-read Unrestricted online access
Summary
This invention is directed to methods and reagents useful for sequencing nucleic acid targets utilizing sequencing by hybridization technology comprising probes, arrays of probes and methods whereby sequence information is obtained rapidly and efficiently in discrete packages. That information can be used for the detection, identification, purification and complete or partial sequencing of a particular target nucleic acid. When coupled with a ligation step, these methods can be performed under a single set of hybridization conditions. The invention also relates to the replication of probe arrays and methods for making and replicating arrays of probes which are useful for the large scale manufacture of diagnostic aids used to screen biological samples for specific target sequences. Arrays created using PCR technology may comprise probes with 5'- and/or 3'-overhangs.
Report Numbers
E 1.99:7,319,003
7,319,003
Subject(s)
Note
Published through SciTech Connect.
01/15/2008.
"7,319,003"
"US patent application 09/030,571"
Cantor, Charles R. (Boston, MA); Prezetakiewiczr, Marek (East Boston, MA); Smith, Cassandra L. (Boston, MA); Sano, Takeshi (Waltham, MA).
Funding Information
FG02-93ER61609
View MARC record | catkey: 23501041