Measurements of carbon-14 with cavity ring-down spectroscopy [electronic resource].
- Washington, D.C. : United States. Dept. of Energy, 2015.
Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy
- Physical Description:
- pages 277-280 : digital, PDF file
- Additional Creators:
- Lawrence Livermore National Laboratory
United States. Department of Energy
United States. Department of Energy. Office of Scientific and Technical Information
- Accelerator Mass Spectrometry (AMS) is the most sensitive method for quantitation of <sup>14</sup>C in biological samples. This technology has been used in a variety of low dose, human health related studies over the last 20 years when very high sensitivity was needed. AMS helped pioneer these scientific methods, but its expensive facilities and requirements for highly trained technical staff have limited their proliferation. Quantification of <sup>14</sup>C by cavity ring-down spectroscopy (CRDS) offers an approach that eliminates many of the shortcomings of an accelerator-based system and would supplement the use of AMS in biomedical research. Our initial prototype, using a non-ideal wavelength laser and under suboptimal experimental conditions, has a 3.5-modern, 1-σ precision for detection of milligram-sized, carbon-14-elevated samples. Furthermore, these results demonstrate proof of principle and provided a starting point for the development of a spectrometer capable of biologically relevant sensitivities.
- Published through SciTech Connect.
Nuclear Instruments and Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms 361 C ISSN 0168-583X AM
Presented at: Accelerator Mass Spectrometry 13, Aix en Provence (France), 14-20 Aug 2014.
A. D. McCartt; T. Ognibene; G. Bench; K. Turteltaub.
- Funding Information:
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