Exploring a wider range of Mg–Ca–Zn metallic glass as biocompatible alloys using combinatorial sputtering [electronic resource].
Published
Washington, D.C. : United States. National Nuclear Security Administration, 2017. Oak Ridge, Tenn. : Distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy
In order to bypass the limitation of bulk metallic glasses fabrication, we synthesized thin film metallic glasses to study the corrosion characteristics of a wide atomic% composition range, Mg(35.9-63%)Ca(4.1-21%)Zn(17.9-58.3%), in simulated body fluid. We highlight a clear relationship between Zn content and corrosion current such that Zn-medium metallic glasses exhibit minimum corrosion. In addition, we found higher Zn content leads to a poor in vitro cell viability. Finally, these results showcase the benefit of evaluating a larger alloy compositional space to probe the limits of corrosion resistance and prescreen for biocompatible applications.
Published through SciTech Connect. 06/30/2017. "sand--2017-6779j" "654840" ChemComm 53 59 ISSN 1359-7345; CHCOFS AM Jinyang Li; Forrest S. Gittleson; Yanhui Liu; Jingbei Liu; Ayomiposi M. Loye; Lyndsey McMillon-Brown; Themis R. Kyriakides; Jan Schroers; Andre D. Taylor.