Function and dysfunction of the cochlea : from mechanisms to potential therapies : a subject collection from Cold Spring Harbor perspectives in medicine / edited by Guy P. Richardson, Christine Petit
- Published:
- Cold Spring Harbor, New York : Cold Spring Harbor Laboratory Press, [2019]
- Physical Description:
- viii, 347 pages ; 27 cm
- Additional Creators:
- Richardson, Guy P.
Petit, Christine
- Contents:
- A functional perspective on the evolution of the cochlea / Christine Køppl and Geoffrey A. Manley -- Cochlear frequency tuning and otoacoustic emissions / Christopher A. Shera and Karolina K. Charaziak -- Development and patterning of the cochlea: from convergent extension to planar polarity / Mireille Montcouquiol and Matthew W. Kelley -- Hair-bundle links: genetics as the gateway to function / Guy P. Richardson and Christine Petit -- Function and dysfunction of TMC channels in inner ear hair cells / David P. Corey, Nurunisa Akyuz, and Jeffrey R. Holt -- Molecular structure of the hair cell mechanoelectrical transduction complex / Christopher L. Cunningham and Ulrich Møller -- Molecular composition of vestibular hair bundles / Jocelyn F. Krey and Peter G. Barr-Gillespie -- The tectorial membrane: mechanical properties and functions / Jonathan Sellon, Roozbeh Ghaffari, and Dennis M. Freeman -- Inner hair cell afferent synapses: molecular mechanisms / Walter Marcotti and Saaid Safieddine -- Outer hair cells and electromotility / Jonathan Ashmore -- Efferent inhibition of the cochlea / Paul Albert Fuchs and Amanda M. Lauer -- Inner ear connexin channels: roles in development and maintenance of cochlear function / Fabio Mammano -- The epidemiology of deafness / Abraham M. Sheffield and Richard J.H. Smith -- Ototoxicity: etiology, mechanisms and protective strategies / Cornø J. Kros and Peter S. Steyger -- Interactions between macrophages and the sensory cells of the inner ear / Mark E. Warchol -- Age-related hearing loss / Michael R. Bowl and Sally J. Dawson -- Stem cells and the bird cochlea: where is everybody? / Amanda S. Janesick and Stefan Heller -- Cochlear gene therapies / Lawrence Lustig and Omar Akil -- Toward the optical cochlear implant / Tobias Dombrowski, Vladan Rankovic, and Tobias Moser -- Active biomechanics of sensory hair bundles / Dolores Bozovic -- Cochlear synaptopathy and noise-induced hearing loss / Gabriel Corfas.
- Summary:
- "Complex molecular machinery within the cells of the inner ear allow it to sense sounds of different frequencies and relay information to the brain. This volume examines the nature of this machinery, the cells involved, and how defects in these components lead to deafness"--
- Subject(s):
- ISBN:
- 9781621822790 hardcover ; alkaline paper
1621822796 hardcover ; alkaline paper - Bibliography Note:
- Includes bibliographical references and index.
View MARC record | catkey: 26777200