Actions for Non-Invasive Measures of Neurotoxicity in Terrestrial and Aquatic Oligochaetes

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Non-Invasive Measures of Neurotoxicity in Terrestrial and Aquatic Oligochaetes / CD. Drewes, A. Lingamneni, RW. Rogge

Conference Author
Environmental Toxicology and Risk Assessment: Second Volume (2nd : 1992 : Pittsburgh, PA)
Physical Description
1 online resource (12 pages) : illustrations, figures, tables
Additional Creators
Drewes, CD., Lingamneni, A., Rogge, RW., American Society for Testing and Materials, and ASTM International
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Summary
Terrestrial and aquatic oligochaete worms are uniquely well suited for using non-invasive electrophysiological recordings to examine neurotoxicity effects on giant nerve fiber-mediated escape reflexes. Such recordings are made less than one minute after treatment by placing unanesthetized worms on a printed circuit board grid and obtaining multi-channel recordings of the all-or-none giant nerve fibers spikes evoked in response to light tactile stimulation to the skin. Neural parameters affected by toxicant treatments include medial and lateral giant nerve fiber conduction velocities, and efficacy of central transmission between the medial giant fiber and its associated motor neuron pool. The utility of this approach is discussed in relation to a proposed set of general criteria that may be useful in evaluating measurements of environmental neurotoxicity.
Dates of Publication and/or Sequential Designation
Volume 1993, Issue 1216 (January 1993)
Subject(s)
Other Subject(s)
ISBN
9780803152571 (e-ISBN)
9780803114852
0803114850
Digital File Characteristics
text file PDF
Bibliography Note
Includes bibliographical references 20.
Other Forms
Also available online via the World Wide Web. Tables of contents and abstracts freely available; full-text articles available by subscription.
Full text article also available for purchase.
Also available in PDF edition.
Reproduction Note
Electronic reproduction. W. Conshohocken, Pa. : ASTM International, 1993. Mode of access: World Wide Web. System requirements: Web browser. Access may be restricted to users at subscribing institutions.
Technical Details
Mode of access: World Wide Web.
Source of Acquisition
ASTM International PDF Purchase price USD25.
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