Actions for Use of the Central Mudminnow (Umbra limi) in the Development and Evaluation of a Sister Chromatid Exchange Test for Detecting Mutagens in Vivo

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Use of the Central Mudminnow (Umbra limi) in the Development and Evaluation of a Sister Chromatid Exchange Test for Detecting Mutagens in Vivo / WE. Bishop, LC. Valentine

Conference Author
Aquatic Toxicology and Hazard Assessment (1980 : Philadelphia, Pa.)
Physical Description
1 online resource (10 pages) : illustrations, figures, tables
Additional Creators
Bishop, WE., Valentine, LC., American Society for Testing and Materials, and ASTM International
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Summary
Genetic toxicology is an area of scientific research which is receiving increasing attention. The increasing number of regulations regarding environmental mutagens and carcinogens has stimulated the development of numerous short-term screening test systems capable of detecting these substances. The sister chromatid exchange (SCE) test has become a popular test method both in vitro and in vivo, particularly because of its high sensitivity and relatively simple methodology. SCEs involve the symmetrical exchange of deoxyribonucleic acid (DNA) segments between homologous chromatids which can be readily visualized in appropriately treated and stained metaphase chromosomes. Though the precise mechanism or mechanisms remain unknown, SCE correlates well with, and may be predictive of, genetic damage.
Dates of Publication and/or Sequential Designation
Volume 1982, Issue 766 (January 1982)
Subject(s)
Other Subject(s)
ISBN
9780803148314 (e-ISBN)
9780803107960
080310796X
Digital File Characteristics
text file PDF
Bibliography Note
Includes bibliographical references 27.
Other Forms
Also available online via the World Wide Web. Tables of contents and abstracts freely available; full-text articles available by subscription.
Full text article also available for purchase.
Also available in PDF edition.
Reproduction Note
Electronic reproduction. W. Conshohocken, Pa. : ASTM International, 1982. Mode of access: World Wide Web. System requirements: Web browser. Access may be restricted to users at subscribing institutions.
Technical Details
Mode of access: World Wide Web.
Source of Acquisition
ASTM International PDF Purchase price USD25.
View MARC record | catkey: 27992837