Biological Effects of Corrosion Products from Metals / K. Merritt, SA. Brown

Conference Author:: Corrosion and Degradation of Implant Materials: Second Symposium (2nd : 1983 : Louisville, Kentucky)
Physical Description:: 1 online resource (13 pages) : illustrations, figures, tables
Additional Creators:: Brown, SA., Merritt, K., American Society for Testing and Materials, and ASTM International

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Summary:

Metallic implants inserted into the body will eventually undergo some degradation by a variety of mechanisms including abrasion and corrosion. The biological effects of the material released into the tissue is a subject of much concern and investigation. We have been investigating the ability of the metallic implants upon degradation to stimulate metal sensitivity reactions, and studies have been undertaken in humans and animals to investigate the tissue response to metallic implants in the presence of metal sensitivity. It is apparent that many patients have a sensitivity to the metals in the implants and that the presence of metals in a sensitive animal or human will elicit inflammatory responses and sometimes the formation of foreign body giant cells. This may have an adverse effect on the performance of the implant with pain, swelling, and tissue necrosis at the site and, in some cases, loosening of the implant. Studies on implant site infections revealed that infection rates are altered by the presence of this tissue response.

Dates of Publication and/or Sequential Designation:

Volume 1985, Issue 859 (January 1985)

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Other Subject(s):

ISBN:

9780803149267 (e-ISBN)
9780803104273
0803104278

Digital File Characteristics:

text file PDF

Bibliography Note:

Includes bibliographical references 28.

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Also available online via the World Wide Web. Tables of contents and abstracts freely available; full-text articles available by subscription.
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Also available in PDF edition.

Reproduction Note:

Electronic reproduction. W. Conshohocken, Pa. : ASTM International, 1985. Mode of access: World Wide Web. System requirements: Web browser. Access may be restricted to users at subscribing institutions.

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Mode of access: World Wide Web.

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ASTM International PDF Purchase price USD25.

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