Machine generated contents note: 1.Introduction : the coming of age of the genome -- 2.The logic of aging -- 3.Genome structure and function -- 4.Genome maintenance -- 5.Genome instability and accerated aging -- 6.The aging genome -- 7.From genome to phenome.
Summary
Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the technology has been developed to test this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms.