Occupations and the Risk of Head and Neck Cancer : A Pooled Analysis of the International Head and Neck Cancer Epidemiology (INHANCE) Consortium

Published: 1-May-19.
Physical Description: 1 online resource
Additional Creators: Ahrens, Wolfgang, Boffetta, Paolo, Curado, M. P. (Maria Paula), Khetan, Prerna, Kjaerheim, Kristina, Lagiou, Pagona, Luce, Daniele, Menezes, Ana, Richiardi, Lorenzo, Serraino, Diego, Stucker, Isabelle, and Wunsch-Filho, Victor

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Restrictions on Access: Free-to-read Unrestricted online access
Summary: "Objective:To investigate the associations between head and neck cancer (HNC) risk and occupations.Methods:We harmonized data on occupations in a pooled analysis of 8839 HNC cases and 13,730 controls in International Head and Neck Cancer Epidemiology (INHANCE) consortium. Logistic regression was used to estimate odds ratios (ORs) for associations of occupations and HNC risk. Population attributable fraction (PAF) for occupations was calculated using the formula P_EC×(OR-1)/OR.¹Results:Trend of increasing HNC risk was found with increasing duration of employment for many occupations, including cooks (OR=1.36; 95% confidence interval [CI] 1.09 to 1.68), cleaners (OR=1.38; 95% CI 1.13 to 1.69), painters (OR=1.82; 95% CI 1.42 to 2.35). The PAF for a priori occupations was 14.5% (95% CI 7.1% to 21.9%) for HNC.Conclusions:We found associations between certain occupations and HNC risks, including for subsites, with a duration-response relationship."
Collection: Penn State Faculty and Staff Researcher Metadata Database Collection.
Note: Academic Journal Article
Part Of: Journal of occupational and environmental medicine
61:5, pp. 397-404
1076-2752

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