Introduction: T cells : friends and foes / Nils-Petter Rudqvist, Lorenzo Galluzzi -- 1. Stimulating T cells against cancer with agonist immunostimulatory monoclonal antibodies / Xue Han, Matthew D. Vesely -- 2. T cells and regulated cell death : kill or be killed / Johan Spetz, Adam G. Presser, Kristopher A. Sarosiek -- 3. Macrophages : their untold story in T cell activation and function / Jennifer L. Guerriero -- 4. Metabolism of T lymphocytes in health and disease / TImo Gaber, Yuling Chen, Pierre-Louis Krauß, Frank Buttgereit -- 5. Cancer immunosurveillance by T cells / Samhita Rao, Karim Gharib, Arnold Han -- 6. T lymphocytes as measurable targets of protection and vaccination against viral disorders / Anne Monette, Andrew J. Mouland -- 7. In silico methods for studying T cell biology / Katherine Grzesik, Kevin Eng, Fabien Crauste, Sebastiano Battaglia.
Summary
'Biology of T Cells - Part B, ' Volume 342, the latest release in the International Review of Cell and Molecular Biology series, offers an overview of the major molecular and cellular aspects of T-cell biology and their links to human pathophysiology. Chapters in this release include Metabolism of T lymphocytes in health and disease, T lymphocytes and autoimmunity, Cancer immunosurveillance by T cells, T lymphocytes as targets in viral disorders, Molecular mechanisms underlying pharmacological immunosuppression, T lymphocyte-based immunotherapeutics, In silico methods to analyze T cell biology, and Engineering Platforms for T Cell Modulation. Key Features: Contains individual chapters that focus on one specific facet of the development, phenotype, function, study or pathophysiological relevance of T lymphocytes; Presents the latest release in the International Review of Cell and Molecular Biology series. --
