Actions for Mitogen Activated Protein Kinases Functions in Signal Transduction and Human Diseases
Mitogen Activated Protein Kinases Functions in Signal Transduction and Human Diseases
- Published
- Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
- Physical Description
- 1 online resource (276 p.)
Access Online
- directory.doabooks.org , Open Access: DOAB: description of the publication
- mdpi.com , Open Access: DOAB, download the publication
- Language Note
- English
- Restrictions on Access
- Open Access Unrestricted online access
- Summary
- Mitogen-activated protein kinases (MAPK) are a large family of enzymes that function as signal transducers to regulate a diverse range of physiological responses. However, signaling via extracellular signal-regulated kinase (ERK), c-Jun amino terminal kinase (JNK), and p38 MAPK also underpin many disease processes. This Special Issue provides new insights into how MAPK signaling contributes to specific pathological processes across a range of conditions, including disorders of lung development, type 2 diabetes, proliferative skin diseases, cardiovascular diseases, and neurological diseases.
- Subject(s)
- Other Subject(s)
- angiogenesis
- antimicrobial peptide
- aortic valve sclerosis
- aortic valve stenosis
- apoptosis
- atherosclerosis
- bone remodeling
- bronchopulmonary dysplasia
- cancer
- cancer signaling
- cecropin A
- cell cycle
- Compatibility
- CR
- cytokines
- DAPK
- DOK4
- downregulation
- DUSP1
- ERK
- ERK1/2
- erlotinib
- extracellular signal-regulated kinase 5 (ERK5)
- extracellular signal-regulated kinases 1/2
- FGF-induced signaling
- FR180204
- FRS2
- gastric ulcer
- HPAECs
- hyperoxia
- infantile myofibromatosis
- inflammation
- JNK
- JNKs
- Kv4.2
- MAPK
- MAPK kinetics
- MAPK/PI3K/Akt signaling pathway
- MEK/ERK signaling
- metabolic profiling
- mitochondria
- mitochondrial dysfunction
- mitogen-activated protein kinase pathway (MAPK pathway)
- mitogen-activated protein kinases (MAPKs)
- MKK4
- MKK7
- N-heterocyclic carbene
- n/a
- naphthalimide-metal complex conjugates
- neuro-inflammation
- neurodegeneration
- NF-κB
- osteoclast differentiation
- oxidative stress
- p38
- p38 MAPK
- p38 MAPKs
- p53
- Parkinson's disease
- PC12 cells
- phosphorylation
- platelet-derived growth factor receptor
- porcine intestinal epithelial cell
- protein kinase inhibitors
- protein tyrosine phosphatase interacting protein 51 (PTPIP51)
- protein-protein interaction (PPI)
- psoriasis
- PTPN6
- Rabdosia inflexa
- reactive oxygen species
- receptor tyrosine kinases
- ROS
- SIRT1
- SIRT2
- SR
- SRC
- sunitinib
- T2DM
- targeted therapy
- tight junction protein
- U0126
- ISBN
- 9783039280704
9783039280711
books978-3-03928-071-1 - Collection
- DOAB Library.
- Terms of Use and Reproduction
- Creative Commons https://creativecommons.org/licenses/by/4.0/
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