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Exploring associations between acute dairy cheese consumption and inflammatory plasma cytokine levels as related to microvascular function

Author
Singh, Pritika
Published
[University Park, Pennsylvania] : Pennsylvania State University, 2021.
Physical Description
1 electronic document
Additional Creators
Alexander, Lacy Marie and Schreyer Honors College
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Open Access.
Summary
Cardiovascular disease (CVD) remains the leading cause of death globally. Life style modification, such as dietary interventions are of increasing interest in the reduction of CVD risk. Dietary dairy is of particular interest due to dairy's potential anti-inflammatory effects. The present study examined the effects of an 8-day controlled dairy cheese diet on acute inflammatory states. The findings of this study support that dairy cheese consumption does not cause significant changes in inflammatory states. Additionally, this study found that though pro-inflammatory cytokines were associated with changes in NO-dependent vasodilation, these associations were mediated by dairy cheese under un-matched micronutrient diets. As such, this study identifies dairy cheese as an inexpensive source of protein, which has limited associations with changes in inflammatory state and CVD risk. Though this study did not show significant sodium associated changes in inflammatory state, it does suggest that sodium induced inflammation could be mediated by oxidative stress induced by high sodium diets. Additionally, this study suggests that the mechanisms through which dietary dairy elicits anti-inflammatory effects is multifaceted, and may be depended on the macro-and micro-nutrients of dairy cheese.
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Dissertation Note
B.S. Pennsylvania State University 2021.
Technical Details
The full text of the dissertation is available as an Adobe Acrobat .pdf file ; Adobe Acrobat Reader required to view the file.
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