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Advances in Male Mediated Developmental Toxicity [electronic resource] / edited by Bernard Robaire, Barbara F. Hales

Published:
New York, NY : Springer US : Imprint: Springer, 2003.
Edition:
1st ed. 2003.
Physical Description:
XXVII, 300 pages : online resource
Additional Creators:
Robaire, Bernard, Hales, Barbara F., and SpringerLink (Online service)
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Series:
Contents:
Gender-Specificity of Gamete Susceptibilities to Exposures -- 1. Female-Specific Reproductive Toxicities Following Preconception Exposure to Xenobiotics -- 2. Overview of Male Mediated Developmental Toxicity -- Exposures and Effects: Occupational and Environmental -- 3. Epidemiologic Evidence on Biological and Environmental Male Factors in Embryonic Loss -- 4. Mechanisms of Male Mediated Developmental Toxicity Induced by Lead -- 5. Paternal Exposure to Known Mutagens and Health of the Offspring: -- 6. FISH (Fluorescence In Situ Hybridization) to Detect Effects of Smoking, Caffeine, and Alcohol on Human Sperm Chromosomes -- Markers of Sperm Damage and Germ Line Genotoxicity -- 7. Sperm Nuclear DNA Damage in the Human -- 8. The Human Spermatozoon-Not Waving but Drowning -- 9. Model Systems for Studying Germ Cell Mutagens: From Flies to Mammals -- 10. Germline Mutation Induction at Mouse and Human Tandem Repeat DNA Loci -- 11. PAINT/DAPI Analysis of Mouse Zygotes to Detect Paternally Transmitted Chromosomal Aberrations -- Exposures and Effects: Causes of Cancer and Consequences of Treatment -- 12. Paternal Occupation and Childhood Cancer -- 13. Radiation and Malformations in a Murine Model -- 14. Mechanisms of Action of Cyclophosphamide as a Male-Mediated Developmental Toxicant -- 15. Chromosome Abnormalities in Human Sperm -- Pregnancy Outcome -- 16. Distinguishing between Fertilization Failure and Early Pregnancy Loss when Identifying Male-Mediated Adverse Pregnancy Outcomes -- 17. ICSI, Male Pronuclear Remodeling and Cell Cycle Checkpoints -- 18. Increased Incidence of Malformations in the Offspring of Male Mice Prenatally Exposed to Synthetic Estrogens -- Strategies for Prevention -- 19. Implications of Research in Male-Mediated Developmental Toxicity to Clinical Counsellors, Regulators, and Occupational Safety Officers -- 20. Restoration of Spermatogenesis after Exposure to Toxicants: Genetic Implications -- Future Directions -- 21. Epigenetics: Role of Germ Cell Imprinting -- 22. Efficiency and Safety of Animal Cloning -- Workshop Reports -- 23. Integrating New Tests of Sperm Genetic Integrity into Semen Analysis: Breakout Group Discussion -- 24. Risk Assessment -- 25. Study Designs for the Assessment of Male Mediated Developmental Toxicity -- 26. Translational Research in Male Mediated Developmental Toxicity -- 285 -- 287.
Subject(s):
ISBN:
9781441991904
Digital File Characteristics:
PDF
text file
Part Of:
Springer Nature eBook
View MARC record | catkey: 34517386