Demonstration of a Specific Action of the Thyroid Hormone on the In Vivo Metabolism of Phosphorus; MISE EN EVIDENCE D'UNE ACTION SPECIFIQUE DE L'HORMONE THYROIDIENNE SUR LE METABOLISME DU PHOSPHORE "IN VIVO".

Author:: Ermans, A. M.
Published:: [Place of publication not identified] : [publisher not identified], 1959.
[Oak Ridge, Tennessee] : [U.S. Atomic Energy Commission], 1959.
Physical Description:: microopaque : positive ; 8 x 13 cm

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Summary:

A study was made in the intact cell of the effect of thyroid hormone on the transfer of the phosphate ion through the membrane of the erythrocytes. The investigation was made by raeasuring the rate at which radiophosphorus was leaving the tagged erythrocyte at various stages of thyroid impregnation, both in man and rats. The concertration of the acid-soluble phosphorus in the red cells and the basal metabolism were determined. The increase in the basal metabolism in hyperthyroid humans and rats is associated with a significant increase in the rate at which P/sup 32/ is leaving the erythrocytes. This rate is reduced in human myxedema and in the rat after administration of a thyroid inhibitor. The concentration of the acidsoluble phosphorus undergoes only small modifications. It was established that the rate at which phosphate escapes through the cell membrane varies with the thyroid activity. (J.S.R.)

Report Numbers:

A/CONF.15/P/122

Other Subject(s):

Collection:

U.S. Atomic Energy Commission depository collection.

Note:

NSA number: NSA-13-006076
OSTI Identifier 4293946
Research organization: Inst. Interuniversitaire des Sciences Nucleaires, Brussels.
Research organization: Univ. Libre de Brussels.

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