Actions for THE SOMATIC MUTATION THEORY OF AGING : ITS APPLICATION IN IRRADIATED AND NON-IRRADIATED LIVERS OF MICE

Email RIS file
Bookmark
Report an Issue

THE SOMATIC MUTATION THEORY OF AGING : ITS APPLICATION IN IRRADIATED AND NON-IRRADIATED LIVERS OF MICE

Author
Crowley, C.
Published
United States : [publisher not identified], 1961.
[Oak Ridge, Tennessee] : [U.S. Atomic Energy Commission], 1961.
Physical Description
microopaque : positive ; 8 x 13 cm
Additional Creators
Curtis, H. J.

Availability

I Want It
I Want It

Finding items...

Summary
The introduction of somatic mutations, represented by chromosome aberrations, as a result of radiation in young mice does not immediately produce the conditions of age. Rather they are part of an interacting system whose expression is checked in more youthful and vigorous stages by countering factors. In the non-pathological condition, some cells are lost as the prolonged result of deleterious somatic mutations present in the nuclei. The morphological integrity of chromosomes during several months of chronic gamma radiation is maintained. Severely damaged cells that have been exposed to fast neutrons can recover their ability to divide. The somatic mutation theory evidenced by the occurrence of chromosome aberrations with age is applicable in liver cells of cortrol mice, and is regarded as a measure of the inherited rate of aging. (auth)
Report Numbers
BNL-6165
Other Subject(s)
Collection
U.S. Atomic Energy Commission depository collection.
Note
DOE contract number: AT(30-2)-GEN-16
NSA number: NSA-17-007788
OSTI Identifier 4744394
Research organization: Brookhaven National Lab., Upton, N.Y.
View MARC record | catkey: 38680359