BASIC MECHANISMS IN THE RADIATION CHEMISTRY OF PROTEINS AND NUCLEIC ACIDS

Author: Luse, R. A.
Published: United States : [publisher not identified], 1963.
[Oak Ridge, Tennessee] : [U.S. Atomic Energy Commission], 1963.
Physical Description: microfiche : negative ; 8 x 13 cm

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Summary

From Conference on Basic Mechanisms in the Radiation Chemistry of Aqueous Media, Gatlinburg, Tenn., May 1963. Basic mechanisms involved in the radiation chemistry of proteins and nucleic acids are discussed. Various hypotheses that have been proposed to explain quantitatively the effects of ionizing radiations on simple biological systems are reviewed, with emphasis on the hit and target theories and the hypothesis of diffusing agents or indirect action. Data are summarized from a number of studies on the radiosensitivity of enzymes and nucleic acids. It is concluded that any particular mechanism proposed for enzymes and nucleic acids will give only a part of the radiobiological effect in a living cell and that the structural organization of the cell overrides any proposal in which one mechanism operating for one cellular component is considered the one effect of radiation in the cell. (C.H.)

Report Numbers

CONF-81-5

Other Subject(s)

Collection

U.S. Atomic Energy Commission depository collection.

Note

DOE contract number: AT(40-1)-1833
NSA number: NSA-18-011627
OSTI Identifier 4107550
Research organization: Puerto Rico Nuclear Center, Mayaguez.

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