Front Matter -- Infectious Disease Drugs. Relebactam (Recarbrio), A β-Lactamase Inhibitor for the Treatment of cIAI/cUTI/HABP/VABP / Dexi Yang -- Vaborbactam (in Combination with Meropenem as Vabomere), a Non-β-Lactam β-Lactamase Inhibitor for Treatment of Complicated Urinary Tract Infections and Pyelonephritis. / Brett C Bookser, K Raja Reddy, Serge H Boyer, Scott J Hecker -- Baloxavir Marboxil (Xofluza), A Cap-Dependent Endonuclease Inhibitor for Treating Influenza / Yong-Jin Wu -- Process Chemistry Development of the HIV Protease Inhibitor Drug Kaletra: A Mixture of Ritonavir and Lopinavir / Daniel A Dickman -- Eravacycline (Xerava), A Novel and Completely Synthetic Fluorocycline Antibiotic / Jie Jack Li -- Albuvirtide (Aikening), A gp41 Analog as an HIV-1 Fusion Inhibitor / Yvonne M Angell, Wendy J Hartsock, Timothy M Reichart -- Cancer Drugs. Darolutamide (Nubeqa); An Androgen Receptor Antagonist for Treating Nonmetastatic, Castration-Resistant Prostate Cancer / Dao-Qian Chen, Ji Zhang -- Venetoclax (Venclexta): A BCL-2 Antagonist for Treating Chronic Lymphocytic Leukemia / Nadia M Ahmad, Jie Jack Li -- Osimertinib (Tagrisso), A Potent and Selective Third-Generation EGFR Inhibitor for the Treatment of Both Sensitizing and T790M-Resistance Mutations / Fengtao Zhou, Ke Ding -- Sotorasib (LUMAKRAS), An Irreversible Covalent Inhibitor of KRAS G12C / Brian A Lanman, Andrew T Parsons -- Lorlatinib (Lorbrena), An ALK Inhibitor for Treating NSCLC / Ruby M Aaron, Hayden K Low, Benjamin T Sokol, Amy B Dounay -- Niraparib (Zejula), A Small Molecule, PARP1/2 Inhibitor for Treating Breast, Ovarian, and Pancreatic Cancers / Raymond Ng -- Selinexor (Xpovio), An XPO1 Inhibitor and A New Class of Therapeutics for Treating Multiple Myeloma / John Mancuso -- CNS Drugs. Sage 217 (Zuranolone) for Treatment of Major Depressive Disorder / Richard T Beresis -- Risdiplam (Evrysdi), A Small Molecule, SMN2 -Directed RNA Splicing Modifier for Treating Spinal Muscular Atrophy / Jie Jack Li -- Miscellaneous Drugs. Esaxerenone (Minnebro), An Oral, Non-steroidal, Selective Mineralocorticoid Receptor Blocker for the Treatment of Essential Hypertension / Narendra B Ambhaikar -- Voclosporin (Lupkynis), A Macrocyclic Peptide Inhibitor of Calcineurin for the Treatment of Lupus Nephritis / Yan Wang -- Computer-Aided Drug Design / Jinxia N Deng -- Index
