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Cell therapy for lung disease / editor, Julia Polak

Published
London : Imperial College Press, [2010]
Copyright Date
©2010
Physical Description
1 online resource (xxiv, 504 pages) : illustrations (some color)
Additional Creators
Polak, Julia M.
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Contents
A general review of the current knowledge of stem cell therapy for lung disorders / Daniel J. Weiss -- Development of the lung : clues for regeneration and repair / Sheila G. Haworth and Alison A. Hislop -- Epithelial-mesenchymal interactions during lung development and their potential relevance to lung repair / Alexandra Firsova [and others] -- Epithelial progenitor cells of the mammalian lung / Roxana M. Teisanu, Joshua C. Snyder and Barry R. Stripp -- Safety of exogenous stem cells / Elizabeth K. Sage, Michael R. Loebinger and Sam M. Janes -- Lung stem cell bioprocessing : fundamentals of producing lung cells / Siti Norhayati Ismail, Julia M. Polak and Anastasios Mantalaris -- Lung repair and regeneration -- animal models / Hiroshi Kubo -- Fibrocytes (reactive or reparative) / Alberto Bellini and Sabrina Mattoli. and Three-dimensional pulmonary constructs / Christine M. Finck, Blair Roszell and Peter I. Lelkes -- Stem cells as vehicles for gene therapy in lung repair / Shirley H.J. Mei and Duncan J. Stewart -- Repair of the lung epithelium in cystic fibrosis / Viranuj Sueblinvong and Daniel J. Weiss -- Pulmonary hypertension and stem cell therapy / Manoj M. Lalu, Rohit Moudgil and Duncan J. Stewart -- Molecular induction of alveolar regeneration / Matthew Hind and Siân Stinchcombe -- Assessment of cell engraftment / Robert Zweigerdt and William Rust -- In vivo imaging for cell therapy / Richard Newton and Guang-Zhong Yang -- Haematopoietic transplantation and pulmonary chimerism / Benjamin T Suratt -- Stem cells and lung cancer / Arielle C. Lebrenne, Shahriar Islam and Malcolm R. Alison.
Summary
"The use of stem cells to help with lung regeneration and repair is a novel therapy which could help phase out the need for conventional surgical or pharmacological approaches currently employed to treat diseases of the lung or other organs. The present book explores all avenues of this new form of medical care, moving swiftly, but in depth, from the basic science of lung development, to the analyses of different stem cell types available for regeneration and on to the application of this knowledge base in initial clinical trials. In this volume a stellar group of researchers converge, from different angles, to help towards clarifying the basic mechanisms of lung repair. These range from basic concepts of regeneration and lung development, the analyses of a variety of cell types that may be involved in lung repair, to ways of creating complex lung structures, including artificial and bioartificial lungs. The book offers an insight into repair mechanisms of the diseased lung, the role of specific lung niches and provides information on initial clinical trials as well as the use of stem cells as vehicles for gene therapy. Ingenious technological aspects of assessing stem cell engraftment of stem cell bioprocessing are also included in this volume."--Publisher's website
Subject(s)
ISBN
9781848164406 (electronic bk.)
1848164408 (electronic bk.)
9781848164390
1848164394
Bibliography Note
Includes bibliographical references and index.
View MARC record | catkey: 43167584