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Metrology : from physics fundamentals to quality of life / edited by P. Tavella, M.J.T. Milton and M. Inguscio, directors of the course, and N. De Leo = Metrologia : dalla fisica fondamentale alla qualità della vita / a cura di P. Tavella, M.J.T. Milton e M. Inguscio, direttori del corso, e di N. De Leo

Conference Author
International School of Physics "Enrico Fermi" (196th : 2016 : Varenna, Italy)
Additional Titles
Metrologia : dalla fisica fondamentale alla qualità della vita
Published
Amsterdam, Netherlands : IOS Press, 2017.
Physical Description
1 online resource
Additional Creators
Tavella, P. (Patrizia), Milton, M. J. T. (Martin J. T.), Inguscio, M., and De Leo, N. (Natascia)
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Contents
Title Page; CONTENTS; Preface; Course group shot; MODULE I. METROLOGY FOR QUALITY OF LIFE; Reference methods and commutable reference materials for clinical measurements; 1. Introduction; 1.1. Importance of medical tests reliability; 1.2. Role of a national metrology institute in bioanalysis; 1.3. Examples of projects undertaken in LNE (France); 1.4. Regulatory drivers and traceability chains in laboratory medicine; 1.5. JCTLM; 1.6. Accreditation according to ISO 15189; 2. Importance of reference methods in EQAS; 3. Importance of commutability; 3.1. Why commutability matters., 3.2. Principle of commutability assessment; 4. Conclusions and perspectives; Reference measurement systems for biomarkers: Towards biometrology; 1. Introduction; 2. Metabolites and small molecules; 2.1. Kidney disease: creatinine; 2.2. Diabetes mellitus: glucose; 3. Peptides and proteins; 3.1. Absolute quantification of peptides and proteins; 3.2. Diabetes mellitus: HbA1c; 3.3. Sepsis and antimicrobial resistance: Procalcitonine; 3.4. Alzheimer's disease: amyloid beta & tau; 3.5. Iron-related disorders: hepcidin; 4. Lipids and lipoproteins., 4.1. Cardiovascular diseases: cholesterol, triglycerides, LDL-C and HDL-C; 4.2. Lipoprotein particle concentration: beyond LDL-C in CVD risk assessment; 5. Conclusion; SI traceable measurements of the Earth from space to monitor and mitigate against climate change; 1. Introduction; 1.1. Climate; 1.2. Earth Observation data quality; 1.3. Sensor post launch Calibration and Validation (Cal/Val); 1.4. Summary; 2. Key climate parameters; 2.1. Essential Climate Variables (ECV); 2.2. Earth Radiation Budget (ERB); 2.3. Solar variability; 2.3.1. Total Solar Irradiance (TSI)., 2.3.2. Solar spectral irradiance (SSI); 2.4. Climate feedbacks; 2.4.1. Introduction; 2.4.2. Cloud feedback on climate; 3. Establishing SI traceability for the Earth observing system; 3.1. Introduction; 3.2. Near simultaneous overpass calibrations (SNO); 3.3. Reference standard calibration test sites; 3.4. Lunar calibration; 3.5. Dominant sources of uncertainty; 3.6. Radiometric accuracy and traceability to SI; 4. Traceable Radiometry Underpinning Terrestrial- and Helio-Studies (TRUTHS): an NMI in space; 4.1. Mission requirements and objectives; 4.2. TRUTHS instrumentation., 4.2.1. Calibration system; 4.3. On-board calibration methods; 4.3.1. Overview; 4.3.2. Step 1: Calibration of TR against CSAR using LDs; 4.3.3. Step 2: HIS (Earth radiance view) calibrated against the TR at each LD wavelength (radiance mode); 4.3.4. Step 3: HIS (Earth radiance view) calibrated at intermediate wavelengths with a lamp; 4.3.5. Step 4: Measurements of the Earth and Sun; 4.3.6. Summary; 5. Conclusions; Amount of substance -- the Avogadro constant and the SI unit ""mole; 1. Introduction; 2. History; 3. The mole as an SI unit in chemistry; 4. Realization and dissemination., and 4.1. Primary standards as reference points.
Subject(s)
Genre(s)
ISBN
9781614998181 (electronic bk.)
1614998183 (electronic bk.)
9781614998174
1614998175
9788874381098 (Società italiana di fisica)
8874381093 (Società italiana di fisica)
Note
"Varenna on Lake Como, Villa Monastero, 27 June-6 July 2016."
Bibliography Note
Includes bibliographical references.
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